James UrbaniakDr. Venture / Phantom Limb / Jonas Venture Jr. (voice)
Patrick WarburtonBrock Samson (voice)
Michael SinterniklaasDean Venture (voice)
Doc HammerDr. Mrs. The Monarch / Henchman 21 / Shoreleave / Billy Quizboy / Dermott / Red Mantle / Rose / Ward (voice)
Christopher McCullochHank Venture / The Monarch / Sgt. Hatred / Hunter Gathers / Pete White / Watch (voice)
Nina AriandaMantilla (voice)